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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR1
All Species:
10
Human Site:
S1527
Identified Species:
16.92
UniProt:
Q9H583
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H583
NP_060542.4
2144
242370
S1527
F
M
S
Q
L
L
S
S
N
N
F
L
K
K
V
Chimpanzee
Pan troglodytes
XP_001156974
2144
242420
S1527
F
M
S
Q
L
L
S
S
N
N
F
L
K
K
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536334
2141
242568
T1527
M
S
Q
L
L
A
S
T
R
F
I
R
K
M
V
Cat
Felis silvestris
Mouse
Mus musculus
NP_659084
2143
242053
N1527
M
S
Q
L
L
A
S
N
H
F
L
K
K
V
V
Rat
Rattus norvegicus
NP_001101888
2143
241191
N1527
M
A
Q
L
L
A
S
N
H
F
L
K
K
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422958
2155
244590
S1539
F
M
S
Q
L
L
T
S
Q
S
L
V
K
K
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SY48
2159
242032
L1522
S
I
S
F
M
A
Q
L
L
A
S
D
G
F
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM75
2096
237201
K1479
N
E
W
E
K
K
M
K
R
P
D
P
N
E
L
Honey Bee
Apis mellifera
XP_393800
2028
231830
I1417
D
S
D
Q
V
D
E
I
R
P
Y
Y
D
Q
L
Nematode Worm
Caenorhab. elegans
Q23495
1650
185210
R1091
T
K
S
E
E
K
M
R
M
C
Q
N
S
A
Y
Sea Urchin
Strong. purpuratus
XP_794611
1635
181917
V1076
E
L
V
D
S
E
I
V
L
S
S
L
L
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8Z4
2001
224001
R1418
M
D
L
S
I
Y
F
R
V
V
T
S
L
L
Q
Baker's Yeast
Sacchar. cerevisiae
P42945
1769
200063
E1210
C
I
T
S
Q
E
N
E
E
A
S
D
S
E
T
Red Bread Mold
Neurospora crassa
Q7RZM8
1788
196873
L1229
A
Q
L
L
E
G
V
L
T
L
A
G
T
V
K
Conservation
Percent
Protein Identity:
100
99.5
N.A.
89.7
N.A.
83.8
84.9
N.A.
N.A.
65.5
N.A.
54.5
N.A.
28.6
30.5
21.1
24.4
Protein Similarity:
100
99.8
N.A.
95
N.A.
92.1
92.7
N.A.
N.A.
80.5
N.A.
73
N.A.
49.4
50.8
38.9
43.2
P-Site Identity:
100
100
N.A.
26.6
N.A.
26.6
26.6
N.A.
N.A.
66.6
N.A.
13.3
N.A.
0
6.6
6.6
6.6
P-Site Similarity:
100
100
N.A.
33.3
N.A.
40
40
N.A.
N.A.
86.6
N.A.
26.6
N.A.
20
33.3
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
21.2
23
Protein Similarity:
N.A.
N.A.
N.A.
43.4
40.2
42.2
P-Site Identity:
N.A.
N.A.
N.A.
0
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
26.6
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
29
0
0
0
15
8
0
0
8
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
8
8
8
8
0
8
0
0
0
0
8
15
8
8
0
% D
% Glu:
8
8
0
15
15
15
8
8
8
0
0
0
0
15
0
% E
% Phe:
22
0
0
8
0
0
8
0
0
22
15
0
0
8
0
% F
% Gly:
0
0
0
0
0
8
0
0
0
0
0
8
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% H
% Ile:
0
15
0
0
8
0
8
8
0
0
8
0
0
0
0
% I
% Lys:
0
8
0
0
8
15
0
8
0
0
0
15
43
22
8
% K
% Leu:
0
8
15
29
43
22
0
15
15
8
22
22
15
8
22
% L
% Met:
29
22
0
0
8
0
15
0
8
0
0
0
0
8
0
% M
% Asn:
8
0
0
0
0
0
8
15
15
15
0
8
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
15
0
8
0
0
0
% P
% Gln:
0
8
22
29
8
0
8
0
8
0
8
0
0
8
8
% Q
% Arg:
0
0
0
0
0
0
0
15
22
0
0
8
0
0
0
% R
% Ser:
8
22
36
15
8
0
36
22
0
15
22
8
15
0
0
% S
% Thr:
8
0
8
0
0
0
8
8
8
0
8
0
8
0
8
% T
% Val:
0
0
8
0
8
0
8
8
8
8
0
8
0
22
50
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
8
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _